Clinical & Experimental Ophthalmology

Biography

Biography: Syed Shoeb Ahmad

Abstract

The trabecular meshwork is the single most important structure which controls the amount of aqueous humor exiting the eye. Thus, most types of glaucoma are caused by a dysfunction in this area. It is interesting to recap the newer concepts in aqueous humor outflow and their control by structures situated in this part of the eye. This presentation shall be answering pertinent questions related to pathophysiological mechanisms which modulate aqueous outflow and regulate the IOP and how an understanding of these processes is helping in the development of newer modalities to manage glaucoma. Subsequent to our understanding of the mechanisms of aqueous outflow, we shall take a look at the medications which have been studied to control aqueous humor outflow. These agents are used to perform what is being called “pharmacologic trabeculectomy”. Conventionally, anti-glaucoma agents reduce intra-ocular pressure by decreasing aqueous production or by increasing aqueous outflow through the unconventional ciliary body pathway. However, there is a group of agents which have been investigated for their role in increasing aqueous outflow through the trabecular meshwork. Thus, this presentation shall be focusing on basic pathophysiology of aqueous outflow as well as “pharmacologic trabeculectomy” to manage intra-ocular pressure more physiologically.