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Sameen Afzal Junejo

Sameen Afzal Junejo

Liaquat University of Medical and Health Sciences
Pakistan

Title: Role of oral Rifampcin in central serous chorioretinopathy (CSCR): Study of 31 cases

Biography

Biography: Sameen Afzal Junejo

Abstract

Central serous chorioretinopathy (CSCR) is characterized by accumulation of fluid in between sensory retina and retinal pigment epithelium. Chronic CSCR present with frequent exacerbations and a poor visual prognosis. Various therapeutic measures are available for recent onset and recurrent/chronic CSR. Thus, novel therapies to combat this frustrating disorder are needed. We will present fifteen cases with recent and chronic CSCR treated with oral Rifampcin that completely resolved with 1 month of oral rifampcin therapy. As a cytochrome P450, 3A4 inducer, rifampin is thought to favorably alter the metabolism of endogenous steroids, thereby leading to an improvement in CSCR manifestations. The study of 31 cases of CSCR treated with half adult dose oral Rifampcin will be presented.