Roberto Pinelli
SERI, Switzerland
Title: Long-term results of accelerated trans-epithelial cross-linking for keratoconus with osmotic riboflavin solution (ParacelTM)
Biography
Biography: Roberto Pinelli
Abstract
Aim: The aim is to present the long-term results of accelerated transepithelial cross-linking (CXL) for keratoconus with osmotic riboflavin solution. Methods: Patient with progressive keratoconus had accelerated transepithelial CXL. Visual and refractive outcomes and the endothelial cell density /ECD) were evaluated preoperatively and postoperatively. Results: Thirty-five patients were examined unilaterally; postoperatively 35 eyes were evaluated at 3 months, 6 months, 1 year and 2 years form the treatment. No intraoperative or postoperative complications occurred. The mean uncorrected distance visual acuity improved significantly form 1.12 ± 0.60 logMAR preoperatively to 0.68 ± 0.49 logMAR at the last follow up and the mean corrected visual acuity form 0.37 ± 0.25 logMAR to 0.09 ± 0.15 logMAR, respectively. The mean steep and the mean flat keratometry readings decreased significantly form 54.71 ± 5.26 diopters (D) and 46.82 ± 3.29, respectively, preoperatively to 46.82 ± 3.69 D and 44.93 ± 3.61 D, respectively, at the last follow-up. The mean corneal astigmatism improved significantly from -6.75 ± 4.38 D preoperatively to -2.50 ± 3.10 D at the last follow-up. No significant ECD alteration occurred. Conclusion: Accelerated trans-epithelial CXL was effective and safe in keratoconic patients over a long-term follow-up.